Brief Summary
The purpose of this study is to determine whether stress echocardiography or computed tomography (CT) of the heart is better at diagnosing emergency room chest pain patients to select appropriate candidates for hospitalization and further work-up.
Brief Title
Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain
Categories
Completion Date
Completion Date Type
Actual
Conditions
Chest Pain
Angina
Angina Pectoris
Coronary Artery Disease
Eligibility Criteria
Inclusion Criteria:
* Presentation to the Emergency Department with chest pain
* Low-to-intermediate risk of coronary disease per Diamond-Forrester criteria
* Free of known coronary artery disease
Exclusion Criteria:
* Inability to undergo both stress echo or coronary CT for any reason
* Contraindication to intravenous iodinated contrast
* Dysrhythmia precluding EKG gating
* Heart rate greater than 60 with contraindication to beta blockers
* Administration of beta blockers within the last 12 hours
* Known severe cardiac valvular disease or pulmonary hypertension
* Stress echocardiography, coronary CT or catheterization within the last 6 months
* Presentation to the Emergency Department with chest pain
* Low-to-intermediate risk of coronary disease per Diamond-Forrester criteria
* Free of known coronary artery disease
Exclusion Criteria:
* Inability to undergo both stress echo or coronary CT for any reason
* Contraindication to intravenous iodinated contrast
* Dysrhythmia precluding EKG gating
* Heart rate greater than 60 with contraindication to beta blockers
* Administration of beta blockers within the last 12 hours
* Known severe cardiac valvular disease or pulmonary hypertension
* Stress echocardiography, coronary CT or catheterization within the last 6 months
Inclusion Criteria
Inclusion Criteria:
* Presentation to the Emergency Department with chest pain
* Low-to-intermediate risk of coronary disease per Diamond-Forrester criteria
* Free of known coronary artery disease
* Presentation to the Emergency Department with chest pain
* Low-to-intermediate risk of coronary disease per Diamond-Forrester criteria
* Free of known coronary artery disease
Gender
All
Gender Based
false
Keywords
stress echocardiography
coronary ct angiography
Healthy Volunteers
No
Last Update Post Date
Last Update Post Date Type
Actual
Last Update Submit Date
Minimum Age
30 Years
NCT Id
NCT01384448
Org Class
Other
Org Full Name
Montefiore Medical Center
Org Study Id
MMC-11-03-107
Overall Status
Completed
Phases
Not Applicable
Primary Completion Date
Primary Completion Date Type
Actual
Official Title
A Randomized Trial Comparing Coronary CT Angiography and Stress Echocardiography for Evaluation of Low-to-Intermediate Risk Emergency Department Chest Pain Patients
Primary Outcomes
Outcome Measure
Hospital admission
Outcome Time Frame
30 days
Secondary Ids
Secondary Id
11SDG7380006
Secondary Outcomes
Outcome Time Frame
30 days
Outcome Measure
Emergency Department length of stay
Outcome Time Frame
30 days
Outcome Measure
Hospital length of stay
Outcome Time Frame
30 days
Outcome Measure
Estimated cost of initial care
Outcome Time Frame
30 days and 1 year
Outcome Measure
Repeat visits to the Emergency Department
Outcome Time Frame
30 days and 1 year
Outcome Measure
Death
Outcome Time Frame
30 days and 1 year
Outcome Measure
Non-fatal myocardial infarction
Start Date
Status Verified Date
First Post Date
First Post Date Type
Estimated
First Submit Date
First Submit QC Date
Std Ages
Adult
Older Adult
Maximum Age Number (converted to Years and rounded down)
999
Minimum Age Number (converted to Years and rounded down)
30
Investigators
Investigator Type
Principal Investigator
Investigator Name
Jeffrey Levsky
Investigator Email
jlevsky@montefiore.org
Investigator Phone