Brief Summary
This research asks whether coronary calcium scoring, a non-invasive test based on computed tomography scanning, is a better way to diagnose chest pain patients than other currently used methods. Three of four patients will undergo calcium scoring and the remaining patients will receive standard care.
Brief Title
Coronary Calcium Scoring Versus Standard Care for Emergency Department Chest Pain Patients
Completion Date
Completion Date Type
Estimated
Conditions
Chest Pain
Eligibility Criteria
Inclusion Criteria:
* complaint of chest pain or pressure
* intermediate risk by HEART score
* clinical indication for non-invasive cardiac imaging
* free of known coronary artery disease
Exclusion Criteria:
* hemodynamic instability
* electrocardiogram suggestive of acute ischemia or myocardial infarction
* unremitting chest pain
* serum troponin levels greater than three times the laboratory threshold
* unable to give his/her own written, informed consent
* pregnant women
* weight \> 182 kg
* unable to lie supine for scan
* coronary calcium score, coronary CTA or non-contrast thoracic CT within the last year and available for review
* unable to comply with 30 day follow-up
* complaint of chest pain or pressure
* intermediate risk by HEART score
* clinical indication for non-invasive cardiac imaging
* free of known coronary artery disease
Exclusion Criteria:
* hemodynamic instability
* electrocardiogram suggestive of acute ischemia or myocardial infarction
* unremitting chest pain
* serum troponin levels greater than three times the laboratory threshold
* unable to give his/her own written, informed consent
* pregnant women
* weight \> 182 kg
* unable to lie supine for scan
* coronary calcium score, coronary CTA or non-contrast thoracic CT within the last year and available for review
* unable to comply with 30 day follow-up
Inclusion Criteria
Inclusion Criteria:
* complaint of chest pain or pressure
* intermediate risk by HEART score
* clinical indication for non-invasive cardiac imaging
* free of known coronary artery disease
* complaint of chest pain or pressure
* intermediate risk by HEART score
* clinical indication for non-invasive cardiac imaging
* free of known coronary artery disease
Gender
All
Gender Based
false
Keywords
chest pain
calcium score
coronary calcium score
coronary calcium scoring
calcium scoring
cacs
ccs
Healthy Volunteers
No
Last Update Post Date
Last Update Post Date Type
Actual
Last Update Submit Date
Minimum Age
21 Years
NCT Id
NCT02828761
Org Class
Other
Org Full Name
Montefiore Medical Center
Org Study Id
2015-4993
Overall Status
Withdrawn
Phases
Not Applicable
Primary Completion Date
Primary Completion Date Type
Estimated
Official Title
A Randomized Controlled Trial of Early Coronary Calcium Scoring and Standard Care in Emergency Department Chest Pain Patients
Primary Outcomes
Outcome Description
number of patients with death, non-fatal heart attack, non-fatal stroke, non-fatal cardiac arrest
Outcome Measure
Major Adverse Cardiovascular Events
Outcome Time Frame
30 days
Secondary Outcomes
Outcome Description
emergency department and inpatient
Outcome Time Frame
through completion of emergency department stay for each patient, an average of six hours and through completion of hospitalization, an average of two days
Outcome Measure
Length of Stay
Start Date
Start Date Type
Estimated
Status Verified Date
First Post Date
First Post Date Type
Estimated
First Submit Date
First Submit QC Date
Std Ages
Adult
Older Adult
Maximum Age Number (converted to Years and rounded down)
999
Minimum Age Number (converted to Years and rounded down)
21
Investigators
Investigator Type
Principal Investigator
Investigator Name
Jeffrey Levsky
Investigator Email
jlevsky@montefiore.org
Investigator Phone