Brief Summary
The purpose of this study is to collect and store brain tissue samples and blood from children with brain cancer that will be tested in the laboratory. Collecting and storing samples of tumor tissue and blood from patients to test in the laboratory may help the study of cancer in the future.
Brief Title
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
Detailed Description
OBJECTIVES:
I. Collect brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children?s Oncology Group institutions.
II. Provide a repository for long-term storage of specimens from these patients.
III. Make these specimens available to qualified researchers to understand the biology of pediatric brain tumors.
OUTLINE: This is a multicenter study.
Brain tumor tissue and blood specimens are collected from patients and banked for future study.
I. Collect brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children?s Oncology Group institutions.
II. Provide a repository for long-term storage of specimens from these patients.
III. Make these specimens available to qualified researchers to understand the biology of pediatric brain tumors.
OUTLINE: This is a multicenter study.
Brain tumor tissue and blood specimens are collected from patients and banked for future study.
Categories
Completion Date
Completion Date Type
Actual
Conditions
Childhood Atypical Teratoid/Rhabdoid Tumor
Childhood Central Nervous System Germ Cell Tumor
Childhood Cerebral Anaplastic Astrocytoma
Childhood Cerebral Astrocytoma
Childhood Choroid Plexus Neoplasm
Childhood Craniopharyngioma
Childhood Grade I Meningioma
Childhood Grade II Meningioma
Childhood Grade III Meningioma
Childhood Infratentorial Ependymoma
Childhood Oligodendroglioma
Childhood Supratentorial Ependymoma
Ependymoma
Newly Diagnosed Childhood Ependymoma
Recurrent Childhood Cerebellar Astrocytoma
Recurrent Childhood Cerebral Astrocytoma
Recurrent Childhood Ependymoma
Recurrent Childhood Medulloblastoma
Recurrent Childhood Supratentorial Embryonal Tumor, Not Otherwise Specified
Recurrent Childhood Visual Pathway Glioma
Eligibility Criteria
Inclusion Criteria:
* Diagnosis of brain tumor
* Previously treated at a Children?s Oncology Group (COG) institution
* Patients are eligible at time of diagnosis, second-look surgery, recurrence, or development of a second malignant neoplasm
* Must have brain tumor biological specimens derived from primary tumors of the CNS available for submission
* Diagnosis of brain tumor
* Previously treated at a Children?s Oncology Group (COG) institution
* Patients are eligible at time of diagnosis, second-look surgery, recurrence, or development of a second malignant neoplasm
* Must have brain tumor biological specimens derived from primary tumors of the CNS available for submission
Inclusion Criteria
Inclusion Criteria:
* Diagnosis of brain tumor
* Previously treated at a Children?s Oncology Group (COG) institution
* Patients are eligible at time of diagnosis, second-look surgery, recurrence, or development of a second malignant neoplasm
* Must have brain tumor biological specimens derived from primary tumors of the CNS available for submission
* Diagnosis of brain tumor
* Previously treated at a Children?s Oncology Group (COG) institution
* Patients are eligible at time of diagnosis, second-look surgery, recurrence, or development of a second malignant neoplasm
* Must have brain tumor biological specimens derived from primary tumors of the CNS available for submission
Gender
All
Gender Based
false
Healthy Volunteers
No
Last Update Post Date
Last Update Post Date Type
Actual
Last Update Submit Date
Maximum Age
18 Years
NCT Id
NCT00919750
Org Class
Network
Org Full Name
Children's Oncology Group
Org Study Id
ACNS02B3
Overall Status
Completed
Primary Completion Date
Primary Completion Date Type
Actual
Official Title
A Children's Oncology Group Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimens
Primary Outcomes
Outcome Measure
Collection of brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children?s Oncology Group institutions
Outcome Time Frame
Up to 16 years
Outcome Measure
Creation of a repository for long-term storage of these specimens
Outcome Time Frame
Up to 16 years
Outcome Measure
Making these specimens available to qualified researchers to understand the biology of pediatric brain tumors
Outcome Time Frame
Up to 16 years
Secondary Ids
Secondary Id
NCI-2009-00334
Secondary Id
COG-ACNS02B3
Secondary Id
CDR0000352347
Secondary Id
ACNS02B3
Secondary Id
ACNS02B3
Secondary Id
U10CA098543
Secondary Id
UG1CA189958
Start Date
Start Date Type
Actual
Status Verified Date
First Post Date
First Post Date Type
Estimated
First Submit Date
First Submit QC Date
Std Ages
Child
Adult
Maximum Age Number (converted to Years and rounded down)
18
Minimum Age Number (converted to Years and rounded down)
0
Investigators
Investigator Type
Principal Investigator
Investigator Name
Lisa Gennarini
Investigator Email
lfigueir@montefiore.org
Investigator Phone